In force Publication date 02 Mar 18
Selection of the most appropriate markers of SARMs misuse. The role of physiological and environmental factors
Project description
Project Title: Selection of the most appropriate markers of SARMs misuse. The role of physiological and environmental factors
Researchers: Dr. M. Mazzarino, Prof. F. Botrè
Institution: Federazione Medico Sportiva Italiana, Italy
Year accepted: 2017
Summary: In this project, we plan to extend the data reported in literature by investigating the phase I and phase II metabolism of SARMs (e.g. RAD140, LGD2226, LGD4033) by in vitro assays. The enzymatic isoforms involved in their metabolism together with the effects of physiological and environmental factors will be also investigated. This information will be useful to select the most appropriate marker(s) of use also in the presence of potential confounding factors (e.g., non prohibited drugs).