A high throughput and sensitive method to detect large peptides, > 2kDa, and insulin analogues in urine and plasma

Code: 20A16DE 

Peptides, IGF-1 and insulin analogues have significant ergogenic properties, however, are very difficult to test for in all samples currently tested for in doping control. To date, only a limited number of specific and targeted samples are tested for these substance. We have developed a high-throughput mass-spectrometry method that will enable anti-doping organisations to screen for large peptides, e.g., GHRHs, insulin analogues and IGF-1 on all samples. This method will enable all WADA-accredited laboratories to effectively screen for these substance.

 1.    To validate a high throughput, sensitive, and inexpensive method to screen several classes of large peptides in urine.
2.    To validate a similar method in serum and plasma.
3.    To test the method for detection of insulin analogues from urine and blood samples from diabetic patients.